Royal Air Force Typhoon FGR4s have operated alongside France's air force in a joint strike targeting an subterranean weapons facility in Syrian territory operated by the Islamic State group (IS), according to the UK Ministry of Defence.
The location, pinpointed through surveillance, was assessed as containing munitions and bombs, the announcement noted, and was positioned in mountains just above the ancient city of Palmyra in Syria's central region.
"Our aircraft utilized laser-guided Paveway IV weapons to strike a several approach shafts leading to the depot... preliminary assessments are that the objective was successfully hit," the MoD said.
There was no evidence of any harm to civilians in the operation on Saturday evening and every plane involved returned to base without incident, the MoD added.
The British jets were backed up by a Voyager tanker plane.
Daesh - referred to as Daesh - established extremist governance over parts of both Syria and Iraq before its territorial defeat in 2019.
"This strike shows British leadership, and commitment to operate in unison with our allies, to eliminate any resurgence of the terrorist group and their harmful and extremist ideologies in the area," the British Defence Secretary the minister stated.
UK warplanes have conducted overwatch operations over Syrian airspace to "deter any attempted comeback" of the group following its routing at the climactic battle in Baghuz in 2019, the ministry said.
"I extend gratitude to every member of British forces participating in this mission for their expertise and their courage," the Defence Secretary added. "They were part of a great many UK service members stationed over Christmas and New Year. This mission, to take out dangerous terrorists who threaten our safety, shows how British military are always on standby, throughout the year, keeping Britain secure domestically and powerful internationally."
Last December, the American forces carried out what it described as a "large-scale strike" on Daesh sites in the country, subsequent to an ambush killed two US servicemembers and a civilian linguist in the Palmyra area.
The United Nations estimates IS still has roughly 5-7 thousand combatants in both countries.